Advanced Pathophysiology

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Question 1

Explain the pathophysiology of the three P’s (Polyuria, Polydipsia, polyphagia)with the given diagnosis of type 1 DM

Question2

Explain the genetics relationship nd how this and the environment can contribute to type 1 DM

Question 3

How would you describe the pathophysiology of type 11 Diabetes Mellitus

Question4

What causes hypothyroidism

references should be 2017 to date

Answer preview

Type 2 Diabetes Mellitus (T2DM) is a metabolic health condition resulting from poor insulin secretion by the pancreatic β-cells and abnormalities of the insulin-sensitive tissues to admit insulin. According to Banday et al. (2020), the dysfunctional pancreatic β-cells impair insulin secretion in the first phase of glucose stimulation, thus increasing glucose intolerance. In the second phase, the release of newly produced insulin gets impaired, leading to the accumulation of glucose in the β-cells. Hence, hyperglycemia acts as the central biomarker for T2DM.

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Advanced Pathophysiology