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The case-control study design can be used in the following circumstances. Where acquiring samples from exposed test subjects is either expensive or hard to get, where a certain disease takes a long time to occur or appear, when dealing with a rare disease that would require a considerably large sample, where the test subjects of a disease are dynamic and hard to keep track of for good results, and where there is little information regarding a disease (Park, 2019). The case-control study method evaluates diverse exposures to establish causation.

• What makes the case-control study design so popular?

The case-control study design is popular because it lacks the limitations brought about by the cohort study design. Case-control studies are especially effective when studying rare diseases. This method allows for investigation into diseases

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case-control study design