Nonsteroidal anti-inflammatory drugs

Sally is a 50-year-old female who has been a jogger for several years. She has recently been diagnosed with osteoarthritis. She has been taking ibuprofen for 3 months but states that “it does not help” and hurts her stomach. The health care provider prescribes celecoxib (Celebrex) 100 mg orally twice a day.

  1. What is the first-line therapy for osteoarthritis and the mechanism of action?
  2. Sally expresses concern about all the recent news about heart problems and celecoxib (Celebrex). What information should be included in a teaching plan to help her understand about taking celecoxib and the benefits and risks?
  3. Ibuprofen and celecoxib are both nonsteroidal anti-inflammatory drugs. Explain how they are similar and different

Submission Instructions:

  • Your initial post should be at least 500 words, formatted and cited in current APA style with support from at least 2 academic sources.

Requirements: 500 words   |   .doc file

Answer preview

Both medications are under the category of NSAID drugs used for the treatment of OA, rheumatoid arthritis, and other conditions. Both Celebrex and Ibuprofen are available in generic form. Both drugs help reduce fever and ease pain, swelling, and soreness caused by arthritis (Isola, Matarese, Ramaglia, Cicciù, & Matarese, 2019). On the contrary, the difference between the two is that Celecoxib comes in capsules of 50, 100,200, and 400 mg with a standard dosage of 200 mg daily with food for adults. On the other hand, Ibuprofen comes in tablets of 400 mg, 600 mg, 800 mg. consumed at 200 to 800 mg three to four times a day with food for adults. Another difference is that Celecoxib is in the class of NSAID, and COX-2 inhibitor, while Ibuprofen is only in the class of NSAID.

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Nonsteroidal anti-inflammatory drugs