Mr. Jones is 57-year-old and is a carrier of sickle cell trait; his wife Ms. Jones is 50 years, and she also has sickle cell trait. Use the following questions to guide your genogram. Limit your genogram to 3 generations
How many of the children might be born with sickle cell disease?
How many percent of their children might not be affected?
How many percent might have the sickle cell trait?
Requirements: Depending on the question ask
- How many percent of their children might not be affected?
25% of Mr. Jones’s family’s children will not be affected. This is represented by NN (no blood disorder) in the genetic diagram above.
- How many percent might have the sickle cell trait?
50% of Mr. Jones’s children might have the sickle cell trait. In the genetic diagram above, it is represented by SN (25%) plus NS (25%) to yield 50%. When an offspring inherits one sickle cell gene and one normal gene, they will have a sickle cell trait (SCT) (CDC. (2020, December 14). 50% of the offspring with SCT will not show symptoms of sickle cell disease (SCD),